108525-13-9

Basic information

• Product Name: (1R,4R,5R,9S,11R)-4,5-epoxy-caryophyll-8⁽¹⁴⁾-en-12-oic acid
• Synonyms: (1R,4R,5R,9S,11R)-4,5-epoxy-caryophyll-8⁽¹⁴⁾-en-12-oic acid
• CAS NO: 108525-13-9
• Molecular Weight: 250.338
• Mol File: 108525-13-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,4R,5R,9S,11R)-4,5-epoxy-caryophyll-8⁽¹⁴⁾-en-12-oic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,4R,5R,9S,11R)-4,5-epoxy-caryophyll-8⁽¹⁴⁾-en-12-oic acid(108525-13-9)
• EPA Substance Registry System: (1R,4R,5R,9S,11R)-4,5-epoxy-caryophyll-8⁽¹⁴⁾-en-12-oic acid(108525-13-9)

Safety Data

• Hazardous Substances Data: 108525-13-9(Hazardous Substances Data)

Upstream product

• 87-44-5 β-caryophyllene 

Relevant articles and documents

BIOTRANSFORMATION OF CARYOPHYLLENE BY DIPLODIA GOSSYPINA

Fermentation of caryophyllene with Diplodia gossypina affords a number of products which are all derived from the 4,5-epoxide.Twelve of these are described here for the first time.The main products are 12-hydroxy-4,5-epoxy-caryophyllene and the corresponding acid.On side reactions additional hydroxylations occured or the exo-methylene group was also epoxidized and further degraded.Two rearranged compounds were found, one resulting from an epoxide rearrangement leading to an eight-membered ring, the other one being a cyclization product possessing the rare skeleton of the punctatin antibiotics.