1085288-24-9Relevant academic research and scientific papers
Meroditerpenoids and derivatives from the brown alga Cystoseira baccata and their antifouling properties
Mokrini, Redouane,Mesaoud, Mohammed Ben,Daoudi, Mohammed,Hellio, Claire,Marechal, Jean-Philippe,El Hattab, Mohamed,Ortalo-Magne, Annick,Piovetti, Louis,Culioli, Gerald
, p. 1806 - 1811 (2008)
The brown alga Cystoseira baccata harvested along the Atlantic coasts of Morocco yielded seven new meroditerpenoids (1-4) and derivatives (5-7), whose chemical structures were elucidated mainly by 2D NMR and mass spectrometry. Surprisingly, for all these compounds, which possess a bicyclo[4.3.0]nonane ring system, a trans fusion of the bicyclic system was deduced by stereochemical studies even though such compounds isolated from Cystoseira species are known to have a typical cis orientation for the bridgehead methyls. The antifouling and antibacterial activities of compounds 1-5 and 7 were evaluated, as well as their toxicity toward nontarget species. Compounds 4, 5, and 7 showed antifouling activities against growth of microalgae, macroalgal settlement, and mussel phenoloxidase activity, while being nontoxic to larvae of sea urchins and oysters.
