1085411-81-9

Basic information

• Product Name: (E)-2-(2-styryl-4-(trifluoromethyl)phenyl)pyridine
• Synonyms: (E)-2-(2-styryl-4-(trifluoromethyl)phenyl)pyridine
• CAS NO: 1085411-81-9
• Molecular Weight: 325.333
• Mol File: 1085411-81-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-2-(2-styryl-4-(trifluoromethyl)phenyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(2-styryl-4-(trifluoromethyl)phenyl)pyridine(1085411-81-9)
• EPA Substance Registry System: (E)-2-(2-styryl-4-(trifluoromethyl)phenyl)pyridine(1085411-81-9)

Safety Data

• Hazardous Substances Data: 1085411-81-9(Hazardous Substances Data)

Upstream product

• 140-10-3 (E)-3-phenylacrylic acid 
• 203065-88-7 2-(4-trifluoromethylphenyl)pyridine 
• 536-74-3 phenylacetylene 

Relevant articles and documents

Rhodium-catalyzed decarbonylative direct olefination of arenes with vinyl carboxylic acids

A rhodium(I)-catalyzed direct C-H bond olefination of pyridyl-substituted arenes with readily available vinyl carboxylic acids has been realized. This reaction occurred efficiently without the need for any external oxidant, affording the ortho-olefinated products in high yields and excellent regioselectivities. Diversely substituted vinyl carboxylic acids behaved as efficient olefination reagents under the reaction conditions, and a range of functional groups in both coupling partners was well tolerated. Mechanistic studies indicated that a decarbonylation step is involved in this catalytic process, and pivalic anhydride [(t-BuCO)2O] acts as the activator of the carboxylic acids for the in situ generation of highly active anhydrides.

RuCl3-catalyzed alkenylation of aromatic C-H bonds with terminal alkynes

(Chemical Equation Presented) RuCl3-catalyzed regio- and/or stereoselective alkenylation reactions of a variety of arylpyridines proceeded efficiently with terminal alkynes or allylic compounds in the presence of benzoyl peroxide or benzoic acid.