1085453-57-1

Basic information

• Product Name: 4-(4-fluorotetrahydro-2H-pyran-4-yl)benzenecarbonitrile
• Synonyms: 4-(4-fluorotetrahydro-2H-pyran-4-yl)benzenecarbonitrile
• CAS NO: 1085453-57-1
• Molecular Weight: 205.232
• Mol File: 1085453-57-1.mol

Chemical Properties

• CAS DataBase Reference: 4-(4-fluorotetrahydro-2H-pyran-4-yl)benzenecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-fluorotetrahydro-2H-pyran-4-yl)benzenecarbonitrile(1085453-57-1)
• EPA Substance Registry System: 4-(4-fluorotetrahydro-2H-pyran-4-yl)benzenecarbonitrile(1085453-57-1)

Safety Data

• Hazardous Substances Data: 1085453-57-1(Hazardous Substances Data)

Upstream product

• 1085453-54-8 4-(4-hydroxytetrahydro-2H-pyran-4-yl)benzenecarbonitrile 
• 3058-39-7 4-iodobenzonitrile 
• 29943-42-8 Tetrahydro-4H-pyran-4-one 

Downstream Products

• 1085453-58-2 4-(4-fluorotetrahydro-2H-pyran-4-yl)-N'-hydroxybenzenecarboximide amide 
• 1418297-17-2 4-(4-fluorotetrahydro-2H-pyran-4-yl)benzaldehyde 

Relevant articles and documents

3-(Fluorovinyl)pyrazoles and their use

The present application relates to novel 3-(fluorovinyl)pyrazole derivatives, to processes for their preparation, to their use for treatment and/or prevention of diseases and to their use for the preparation of medicaments for treatment and/or prevention of diseases, in particular for treatment and/or prevention of hyperproliferative and angiogenic diseases and those diseases which arise from metabolic adaptation to hypoxic states. Such treatments can be carried out as monotherapy or also in combination with other medicaments or further therapeutic measures.

HETEROCYCLICALLY SUBSTITUTED ARYL COMPOUNDS AS HIF INHIBITORS

The present application relates to novel aryl compounds with heterocyclic substituents, processes for their preparation, their use for treatment and/or prevention of diseases and their use for the preparation of medicaments for treatment and/or prevention

Substituted heterocyclylbenzylpyrazoles and use thereof

The present application relates to novel substituted 1-[3-(heterocyclyl)benzyl]-1H-pyrazole derivatives, to processes for preparation thereof, to use thereof for treatment and/or prevention of diseases and to use thereof for production of medicaments for treatment and/or prevention of diseases, more particularly for treatment and/or prevention of hyperproliferative and angiogenic diseases and those diseases which arise from metabolic adaptation to hypoxic states. Such treatments can be effected in the form of monotherapy or else in combination with other medicaments or further therapeutic measures.

HETEROAROMATIC COMPOUNDS FOR USE AS HIF INHIBITORS

The present application relates to novel substituted aryl compounds, processes for their preparation, their use for treatment and/or prevention of diseases and their use for the preparation of medicaments for treatment and/or prevention of diseases, in particular for treatment and/or prevention of hyperproliferative and angiogenic diseases and those diseases which arise from metabolic adaptation to hypoxic states. Such treatments can be carried out as monotherapy or also in combination with other medicaments or further therapeutic measures.

HETEROARYL SUBSTITUTED PYRAZOLE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS

This invention relates to novel heteroaryl substituted pyrazole compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients or therapeutic measures.