108574-20-5Relevant articles and documents
Facile Conversion of Aldehydes into 1-Substituted 2-Chloro-3,3-difluoro-2-propen-1-ols with 1,1-Dibromo-1-chloro-2,2,2,-trifluoroethane/Magnesium Reagent
Fujita, Makoto,Hiyama, Tamejiro
, p. 3321 - 3322 (2007/10/02)
Aldehydes RCHO are converted in excellent yields into chlorodifluoroallyl alcohols RCH(OH)CCl=CF2 upon treatment with CClBr2CF3 and magnesium in tetrahydrofuran at 0 deg C.
PRACTICAL WAYS FROM ALDEHYDES TO 2-CHLORO-1,1,1-TRIFLUORO-2-ALKENES AND 2-CHLORO-1,1-DIFLUORO-1-ALKEN-3-OLS
Fujita, Makoto,Hiyama, Tamejiro
, p. 3655 - 3658 (2007/10/02)
A reagent system CF3CCl3/Zn(>2 mol)/Ac2O transformed aldehydes to 2-chloro-1,1,1-trifluoro-2-alkenes exclusively, whereas CF3CCl3/Zn(>2 mol)/AlCl3(cat.) converted aldehydes into 2-chloro-1,1-difluoro-1-alken-3-ols.