1085775-94-5Relevant academic research and scientific papers
Novel naphthoquinone and quinolinedione inhibitors of CDC25 phosphatase activity with antiproliferative properties
Braud, Emmanuelle,Goddard, Mary-Lorene,Kolb, Stephanie,Brun, Marie-Priscille,Mondesert, Odile,Quaranta, Muriel,Gresh, Nohad,Ducommun, Bernard,Garbay, Christiane
experimental part, p. 9040 - 9049 (2009/04/11)
CDC25 phosphatases are considered as attractive targets for anti-cancer therapy. To date, quinone derivatives are among the most potent inhibitors of CDC25 phosphatase activity. We present in this paper the synthesis and the biological evaluation of new q
