108583-15-9Relevant academic research and scientific papers
SELECTIVE HDAC6 INHIBITORS AND USES THEREOF
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Page/Page column 24, (2016/08/10)
The present invention relates to selective Histone deacetylase 6 (HDAC6) inhibitors and compositions containing the same. Methods of treating diseases and conditions wherein inhibition of HDAC6 provides a benefit, like a cell proliferative disease, an aut
Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors
De Vreese, Rob,Van Steen, Nicholas,Verhaeghe, Tom,Desmet, Tom,Bougarne, Nadia,De Bosscher, Karolien,Benoy, Veronick,Haeck, Wanda,Van Den Bosch, Ludo,D'Hooghe, Matthias
supporting information, p. 9868 - 9871 (2015/06/16)
A small library of 3-[(4-hydroxycarbamoylphenyl)aminomethyl]benzothiophenes was prepared and assessed as a novel class of HDAC6 inhibitors, leading to the identification of three representatives as potent and selective HDAC6 inhibitors. Further tests with
Newer Indolylthiazolidinones as Potent Antiinflammatory Agents.
Singh, Inder Pal,Saxena, A. K.,Shanker, K.
, p. 838 - 843 (2007/10/02)
Several new indolylthiazolidinones(III-V) and indolylmethyleneiminobenzoic acid hydrazides(VIII) have been prepared.Out of thirty compounds tested for their antiinflammatory activity against carrageenin-induced rat paw oedema, twenty four compounds show 2
