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2-Pyridinecarboxamide, 3-hydroxy-N-(4-methoxyphenyl)-, also known as 3-hydroxy-N-(4-methoxyphenyl)nicotinamide, is a chemical compound with the molecular formula C13H12N2O3. It is a derivative of nicotinamide, which is a form of vitamin B3. 2-Pyridinecarboxamide, 3-hydroxy-N-(4-methoxyphenyl)- features a pyridine ring with a carboxamide group at the 2-position, a hydroxyl group at the 3-position, and a 4-methoxyphenyl group attached to the nitrogen atom. It is an organic compound with potential applications in pharmaceuticals and chemical research, particularly in the development of new drugs and as a building block for more complex molecules. The compound's structure and properties make it a versatile intermediate in synthetic chemistry, with potential uses in the creation of various biologically active molecules.

1086-62-0

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1086-62-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1086-62-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,8 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1086-62:
(6*1)+(5*0)+(4*8)+(3*6)+(2*6)+(1*2)=70
70 % 10 = 0
So 1086-62-0 is a valid CAS Registry Number.

1086-62-0Downstream Products

1086-62-0Relevant academic research and scientific papers

Antimycobacterial and antifungal isosters of salicylamides

Waisser, Karel,Pe?ina, Milan,Holy, Pavel,Pour, Milan,Bure?, Otakar,Kune?, Ji?í,Klime?ová, V?ra,Buchta, Vladimír,Kubanová, Petra,Kaustová, Jarmila

, p. 322 - 335 (2007/10/03)

A set of 40 derivatives of 3-hydroxypicolinic acid and 2-sulfanylbenzoic acid, isosteric to salicylanilides was synthesized. The compounds were evaluated for in vitro activity against Mycobacterium tuberculosis, Mycobacterium kansasii and Mycobacterium avium, Candida albicans, Candida tropicalis, Candida krusei, Candida glabrata, Trichosporon beigelii, Aspergillus fumigatus, Absidia corymbifera, Trichophyton mentagrophytes and Microsporum gypseum. Structure-activity relationships of antimycobacterial activity and antifungal activity against T. mentagrophytes and M. gypseum were analyzed by the Free-Wilson method. An increase in antimycobacterial activity was observed only for the sulfanylbenzoic acid derivatives, especially those with the benzyl moiety. The antifungal activity was not significant.

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