1086018-77-0Relevant articles and documents
Palladium-catalyzed asymmetric decarboxylative lactamization of γ-methylidene-δ-valerolactones with isocyanates: Conversion of racemic lactones to enantioenriched lactams
Shintani, Ryo,Park, Soyoung,Shirozu, Fumitaka,Murakami, Masataka,Hayashi, Tamio
, p. 16174 - 16175 (2008)
A palladium-catalyzed asymmetric decarboxylative reaction of racemic γ-methylidene-δ-valerolactones with aryl isocyanates has been developed to give enantioenriched 3,3-disubstituted 2-piperidones. High enantioselectivity has been achieved by tuning the e