1086109-83-2Relevant academic research and scientific papers
Three component coupling of α-iminoesters via umpolung addition of organometals: Synthesis of α,α-disubstituted α-amino acids
Dickstein, Joshua S.,Fennie, Michael W.,Norman, Amber L.,Paulose, Betty J.,Kozlowski, Marisa C.
supporting information; experimental part, p. 15794 - 15795 (2009/05/15)
The synthesis of α,α-disubstituted α-amino acids by means of a three component coupling is reported. The coupling occurs through umpolung addition of organometallic reagents to the nitrogen of α-iminoesters. The resulting enolate intermediates subsequentl
