108621-22-3

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 14161-12-7 6-methoxy-2,3-dihydro-phthalazine-1,4-dione 
• 98-80-6 phenylboronic acid 

Downstream Products

• 108618-31-1 7-methoxy-1-phenyl-phthalazine 
• 256443-75-1 1-chloro-6-methoxy-4-phenyl-phthalazine 

Relevant academic research and scientific papers

Design, synthesis and analgesic properties of novel conformationally-restricted N-acylhydrazones (NAH)

A set of six azaheterocycles were designed as conformationnaly-constrained N-acylhydrazones and tested as analgesics.

Phthalazine derivatives phosphodiesterase 4 inhibitors

The present invention provides a compound selected from the group including: 1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-4-phenyl-phthalazine; 4-(3,5-dichloro-pyridin-4-ylmethyl)-7-methoxy-1H-phthalazin-2-carboxylic acid methyl ester; benzyl-{3-{1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-phthalazin-5-yl}-prop-2-ynyl}-methyl-amine; 1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-5-(5-morpholin-4-yl-pent-1-ynyl)-phthalazine dihydrochloride; 3-{1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-phthalazin-5-yl}-prop-2-yn-1-ol; 1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-4-morpholin-4-yl-phthalazine; 1-(3,5-dichloro-pyridin-4-ylmethyl)-6-methoxy-4-(1,2,4)triazol-1-yl-phthalazine; N→O derivatives thereof; and pharmaceutically acceptable salts thereof. The invention also provides a pharmaceutical composition which includes a therapeutically effective amount of the above compound in admixture with a suitable carrier.