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(+)-(R)-2-hydroxy-1,2,2-triphenylethyl N,N-diisopropylcarbamate, also known as R-deprenyl or selegiline, is a pharmaceutical compound with neuroprotective and antioxidant properties. It is a selective and irreversible inhibitor of monoamine oxidase B (MAO-B), an enzyme responsible for breaking down dopamine in the brain. By inhibiting MAO-B, selegiline can increase dopamine levels, making it a promising candidate for the treatment of Parkinson's disease and depression.

1086338-52-4

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1086338-52-4 Usage

Uses

Used in Pharmaceutical Industry:
(+)-(R)-2-hydroxy-1,2,2-triphenylethyl N,N-diisopropylcarbamate is used as a medication for the treatment of Parkinson's disease and depression. It functions as a selective and irreversible inhibitor of monoamine oxidase B (MAO-B), which helps increase dopamine levels in the brain and improve symptoms associated with these conditions.
Used in Neuroprotection:
(+)-(R)-2-hydroxy-1,2,2-triphenylethyl N,N-diisopropylcarbamate is used for its neuroprotective properties, which may contribute to its therapeutic effects in treating Parkinson's disease and depression. Its antioxidant properties also play a role in protecting the brain from oxidative stress and related damage.
Used in Dopamine Regulation:
(+)-(R)-2-hydroxy-1,2,2-triphenylethyl N,N-diisopropylcarbamate is used to regulate dopamine levels in the brain. By inhibiting the enzyme MAO-B, selegiline can help maintain appropriate dopamine concentrations, which is crucial for the management of Parkinson's disease and depression symptoms.

Check Digit Verification of cas no

The CAS Registry Mumber 1086338-52-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,6,3,3 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1086338-52:
(9*1)+(8*0)+(7*8)+(6*6)+(5*3)+(4*3)+(3*8)+(2*5)+(1*2)=164
164 % 10 = 4
So 1086338-52-4 is a valid CAS Registry Number.

1086338-52-4Relevant academic research and scientific papers

Comprehensive experimental and theoretical studies of configurationally labile epimeric diamine complexes of α-lithiated benzyl carbamates

Lange, Heiko,Huenerbein, Robert,Wibbeling, Birgit,Froehlich, Roland,Grimme, Stefan,Hoppe, Dieter

experimental part, p. 2905 - 2918 (2009/04/07)

Different primary benzyl-type carbamates were deprotonated by sec-butyllithium in the presence of a tert-leucinol-derived bis(oxazoline) ligand. The resulting configurationally labile epimeric complexes equilibrated and one diastereomer was strongly favor

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