1086392-03-1

Basic information

• Product Name: (3-Fluoro-2-formyl-phenyl)-carbamic acid tert-butyl ester
• Synonyms: (3-Fluoro-2-formyl-phenyl)-carbamic acid tert-butyl ester;tert-Butyl (3-fluoro-2-formylphenyl)carbamate
• CAS NO: 1086392-03-1
• Molecular Formula: C₁₂H₁₄FNO₃
• Molecular Weight: 239.2428632
• Mol File: 1086392-03-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-Fluoro-2-formyl-phenyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3-Fluoro-2-formyl-phenyl)-carbamic acid tert-butyl ester(1086392-03-1)
• EPA Substance Registry System: (3-Fluoro-2-formyl-phenyl)-carbamic acid tert-butyl ester(1086392-03-1)

Safety Data

• Hazardous Substances Data: 1086392-03-1(Hazardous Substances Data)

Usage

General Description

(3-Fluoro-2-formyl-phenyl)-carbamic acid tert-butyl ester is a chemical compound with the molecular formula C12H14FNO3. It is an ester derivative of (3-fluoro-2-formylphenyl)carbamic acid and is often used in the field of organic synthesis and medicinal chemistry as a building block for creating complex organic compounds. Its tert-butyl ester group makes it a stable and versatile compound that can be used as a precursor for various pharmaceuticals, agrochemicals, and other fine chemicals. It has also shown potential as a therapeutic agent in the treatment of certain diseases and conditions. Overall, this chemical compound exhibits a range of promising properties that make it valuable in the development of new drugs and chemical products.

Upstream product

• 434-76-4 2-amino-6-fluorobenzoic acid 
• 221285-25-2 (2-amino-6-fluorophenyl)methanol 

Downstream Products

• 1605285-59-3 C₁₉H₂₂F₄N₄O₃S 
• 1605288-67-2 tert-butyl (2-((N-(2-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)ethyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamido)methyl)-3-fluorophenyl)carbamate 
• 1605288-65-0 tert-butyl (3-fluoro-2-((N-(2-(tetrahydro-2H-thiopyran-4-yl)ethyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamido)methyl)phenyl)carbamate 
• 1605288-64-9 tert-butyl (3-fluoro-2-(((2-(tetrahydro-2H-thiopyran-4-yl)ethyl)amino)methyl)phenyl)carbamate 

Relevant articles and documents

Pd-Catalyzed Three-Component Domino Reaction of Vinyl Benzoxazinanones for Regioselective and Stereoselective Synthesis of Allylic Sulfone-Containing Amino Acid Derivatives

A Pd-catalyzed, highly regioselective and stereoselective three-component domino allylic substitution/N-H carbene insertion reaction under mild conditions is described. This reaction demonstrates a wide substrate scope and satisfactory functional group tolerance, providing a broad range of allylic sulfone-containing amino acid derivatives. Moreover, DBU mediates highly diastereoselective cross-dehydrogenative coupling annulation of allylic sulfones without using peroxides or any metal oxidants. This developed protocol affords 7-membered ring heterocyclic compounds incorporating both sulfone-containing amino acid esters and one quaternary carbon center. Mechanistic studies indicate that an unusual umpolung of glycine occurred in this annulation.