1086397-52-5Relevant academic research and scientific papers
HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION
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Page/Page column 30, (2009/12/05)
The present invention relates to processes for the preparation of heteroaryl ethers. In some embodiments, the processes relate to cross coupling reactions between triazol-1-yloxy and triazol-1-yl heterocycles with aryl boronic acids. In a further aspect, this invention also relates to compounds that are useful for the treatment of oncological diseases or disorders, and for the treatment of inflammation.
Heteroaryl ethers by oxidative palladium catalysis of pyridotriazol-1-yloxy pyrimidines with arylboronic acids
Bardhan, Sujata,Wacharasindhu, Sumrit,Wan, Zhao-Kui,Mansour, Tarek S.
supporting information; experimental part, p. 2511 - 2514 (2009/10/18)
The oxidative palladium-catalyzed cross-coupling of pyrimidines containing pyridotriazol-1-yloxy (OPt) as either a urea or an amide functional group with arylboronic acids in the presence of Cs2CO3 in DME containing 0.6-1.0% H2
Hydrogen peroxide mediated formation of heteroaryl ethers from pyridotriazol-1-yloxy heterocycles and arylboronic acids
Bardhan, Sujata,Tabei, Keiko,Wan, Zhao-Kui,Mansour, Tarek S.
supporting information; experimental part, p. 5733 - 5736 (2009/12/06)
Pyridotriazol-1-yloxypyrimidine 3 reacts with arylboronic acids under palladium-free, Cs2CO3, (0.8%) H2O2, and DME conditions to produce heteroaryl ethers 4-16 in good yields comparable to the oxidative palladiu
