108644-01-5

Basic information

• Product Name: (1'RS,1''E,2SR,2'E,3SR)-3-<3'-(diphenylphosphinoyl)-1'-methylprop-2'-enyl>-2-methyl-2-(3''-oxobut-1''-enyl)cyclopentan-1-one
• CAS NO: 108644-01-5
• Molecular Weight: 420.488
• Mol File: 108644-01-5.mol

Chemical Properties

• CAS DataBase Reference: (1'RS,1''E,2SR,2'E,3SR)-3-<3'-(diphenylphosphinoyl)-1'-methylprop-2'-enyl>-2-methyl-2-(3''-oxobut-1''-enyl)cyclopentan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1'RS,1''E,2SR,2'E,3SR)-3-<3'-(diphenylphosphinoyl)-1'-methylprop-2'-enyl>-2-methyl-2-(3''-oxobut-1''-enyl)cyclopentan-1-one(108644-01-5)
• EPA Substance Registry System: (1'RS,1''E,2SR,2'E,3SR)-3-<3'-(diphenylphosphinoyl)-1'-methylprop-2'-enyl>-2-methyl-2-(3''-oxobut-1''-enyl)cyclopentan-1-one(108644-01-5)

Safety Data

• Hazardous Substances Data: 108644-01-5(Hazardous Substances Data)

Upstream product

• 1120-73-6 2-methyl-2-cyclopenten-1-one 
• 21860-46-8 (E)-β-acetylvinyl phenyl sulphone 
• 17668-60-9 trans-crotyldiphenylphosphine oxide 
• 4643-20-3 (E)-4-chloro-3-buten-2-one 

Downstream Products

• 122334-22-9 (1RS,1'RS,5SR,7aRS)-1-<3'-(diphenylphosphinoyl)-1'-methylpropyl>-7a-methyl-2,3,5,6,7,7a-hexahydro-1H-inden-5-ol 
• 122334-19-4 (1RS,1'RS,7aRS)-1-<3'-(diphenylphosphinoyl)-1'-methylpropyl>-7a-methyl-1,2,3,6,7,7a-hexahydro-5H-inden-5-one 
• 122334-18-3 (1'RS,2RS,3RS)-3-<3'-(diphenylphosphinoyl)-1'-methylpropyl>-2-methyl-2-(3''-oxobutyl)cyclopentan-1-one 

Relevant articles and documents

Efficient Trapping of Ketone Enolates with Acrylate and β-Sulfonylacrylate Thioesters, β-Sulfonyl-, β-sulfinyl- and β-Chloro-vinyl Ketones; Facile Preparation of a Hydrindanone, cis-Dimethyloctalone, and Unsaturated 1,5-Dicarbonyl Compounds

Tandem conjugate addition-ring closure involving reaction of the lithium enolate arising from conjugate addition of lithiated (E)-but-2-enyldiphenylphosphine oxide to 2-methyl-cyclopent-2-enone with two moles of t-butylthioacrylate generates a hydrindanol

Use of β-Sulfonyl Vinyl Ketones as Equivalents to Vinyl Ketones in Robinson Annelation. Convergent, Highly Stereoselective Preparation of a Hydrindanol Related to Vitamin D from 2-Methylcyclopent-2-enone and Lithiated (E)-But-2-enyldiphenylphosphine Oxide

Conjugate addition of lithiated (E)-but-2-enyldiphenylphosphine oxide (3) to 2-methylcyclopent-2-enone (2) in tetrahydrofuran at -20 deg C generates the enolate 8, which reacts rapidly with a series of β-sulfonyl vinyl ketones to generate unsaturated dike