108656-83-3

Basic information

• Product Name: 1-Propanamine,N-(3-methyl-2(3H)-benzothiazolylidene)-(9CI)
• Synonyms: 1-Propanamine,N-(3-methyl-2(3H)-benzothiazolylidene)-(9CI)
• CAS NO: 108656-83-3
• Molecular Formula: C11H14N2S
• Molecular Weight: 206.30726
• Product Categories: BENZOTHIAZOLE
• Mol File: 108656-83-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Propanamine,N-(3-methyl-2(3H)-benzothiazolylidene)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanamine,N-(3-methyl-2(3H)-benzothiazolylidene)-(9CI)(108656-83-3)
• EPA Substance Registry System: 1-Propanamine,N-(3-methyl-2(3H)-benzothiazolylidene)-(9CI)(108656-83-3)

Safety Data

• Hazardous Substances Data: 108656-83-3(Hazardous Substances Data)

Upstream product

• 615-20-3 2-chlorobenzo[d][1,3]thiazole 
• 24622-33-1 N-propylbenzo[d]thiazol-2-amine 
• 74-88-4 methyl iodide 

Relevant articles and documents

Structure-activity relationship of dihydroimidazo-, dihydropyrimido, tetrahydrodiazepino-[2,1-b]-thiazoles, and -benzothiazoles as an acylation catalyst

Cyclic isothioureas 1, 2, 3, and 4 were synthesized through a four-step procedure from the corresponding ortho-bromoanilines 10 via Pd- or Cu-catalyzed cyclization-benzothiazole formation. Nonbenzo analogues 7, 8, and 9 were synthesized by a condensation reaction of cyclic thioureas 15 and α-bromoacetophenones 14. Investigations of the acylation reactions of 1-phenylethanol with acid anhydrides in the presence of these cyclic isothiourea catalysts revealed their structure-activity relationships. Remarkable electronic effects resulting from substituent(s) on a benzo or phenyl moiety and the influence of the size of the annulating ring were observed. Introduction of an electron-donating substituent(s) enhanced the reaction rate. A few substitution effects on chiral catalysts of type 3 and 7 were also studied.