108692-67-7

Upstream product

• 108661-20-7 ((1R,2S)-1-Ethyl-2-methyl-but-3-enyloxymethyl)-benzene 
• 95273-28-2 <3R,4S>-4-methyl-5-hexen-3-ol 
• 138832-83-4 5R/S,6-isopropylidenedioxy-4S-methyl-3R/S-hexanol benzyl ether 
• 85433-17-6 5R/S,6-isopropylidenedioxy-4S-methyl-3R/S-hexanol 
• 138832-84-5 4R/S-benzyloxy-3S-methyl-1,2R/S-hexanediol 
• 95273-23-7 (3S,4R)-4-Methyl-5-trimethylsilanyl-hex-5-en-3-ol 
• 95273-24-8 (3R,4R)-4-Methyl-5-trimethylsilanyl-hex-5-en-3-ol 
• 108661-19-4 (R)-4-Methyl-5-trimethylsilanyl-hex-5-en-3-one 
• 244171-37-7 (2S,3R)-2-cyanopentan-3-yl acetate 
• 244171-36-6 (2S,3R)-3-hydroxy-2-methylpentanenitrile 
• 111160-14-6 1-(benzyloxy)-1-(prop-2-enyloxy)propane 
• 80060-21-5 1-ethoxy-1-(prop-2-enyloxy)propane 
• 84736-39-0 (Z)-1-(benzyloxy)-1-(prop-1-enyloxy)propane 
• 80060-32-8 (E)-1-(1-Ethoxy-propoxy)-propene 

Downstream Products

• 108661-15-0 3R,S-benzyloxy-2S-methylpentanoic acid 
• 138832-86-7 3R/S-benzyloxy-2S-methylpentanoic acid 3-pentyl ester 

Relevant academic research and scientific papers

Thiocrown ether additive effects on diastereoselectivity of the lipase- catalyzed reaction: Preparation of optically active 3-hydroxy-2- methylalkanenitriles through a double enzymatic reaction strategy

The additive effect on diastereoselectivity towards the lipase-catalyzed hydrolysis of acetates of 3-hydroxy-2-methyl-or 3-hydroxy-2- ethylalkanenitriles has been investigated. Diastereoselectivity was not influenced by thiocrown ether additives, although a significant modification of enantioselectivity was observed. Origin of the diastereoselectivity of the lipase-catalyzed reaction was thus evidently different from that of enantioselectivity. Based on these results, an easy preparation of optically active 3-hydroxy-2-methylpentanenitrile and 3-hydroxy-2-methylbutanenitrile have been demonstrated through lipase-catalyzed reaction by a double enzymatic reaction strategy.

SYNTHESIS OF ALL FOUR POSSIBLE ENANTIOMERS OF SITOPHILATE AGGREGATION PHEROMONE OF THE GRANARY WEEVIL

An efficient synthesis of the 3-pentyl ester of 2S-methyl-3R-hydroxypentanoic acid (sitophilate) and its 2S,3S-, 2R,3R-, and 2R,3S-isomers has been carried out starting from the available 2R-methyl-3-butenyl acetate as sole monochiral precursor.

DIASTEREO- AND ENANTIOSELECTIVE PREPARATION OF β-ALKYLHOMOALLYLIC ALCOHOLS SYNTHESIS OF SERRICORNIN AND CORYNOMYCOLIC ACID

A new and efficient method for the preparation of four possible stereoisomers of β-alkylhomoallylic alcohols 1 has been developed which is based on the diastereoselective addition of nucleophiles to optically active α-alkyl-β-trimethylsilyl-β,γ-unsaturate

DIASTEREOSELECTION IN 1,3-O- TO -C-ALKYL MIGRATION REACTION OF 1-ALKENYL ALKYL ACETALS CATALYZED BY BORON TRIFLUORIDE ETHERATE

Remarkable diastereoselection, with (E)-alkenyl alkyl acetal giving selectively the erythro α-alkyl-β-alkoxyaldehyde, and (Z)-acetal leading preferentially to the threo isomer, is observed in the 1,3-O- to -C-alkyl migration reaction of 1-alkenyl alkyl ac