108694-50-4Relevant academic research and scientific papers
Nickel-Catalyzed Transformations of 2,1-Benzisoxazoles with Organozinc Reagents
Baum, Jonathan S.,Condon, Michael E.,Shook, David A.
, p. 2983 - 2988 (1987)
A novel transformation of 2,1-benzisoxazoles (anthranils) involving nitrogen-oxygen bond rupture with concomitant nitrogen-carbon bond formation by reaction with aryl-, methyl, or 2-thienylzinc chlorides in the presence of nickel catalyst is described.The products of the reaction are o-(substituted-amino)benzaldehydes and benzophenones, precursors of a series of heterocyclic derivatives, including acridines, quinolones, and the novel 7-chloro-1,3-dihydro-1,5-diphenyl-2H-1,4-benzodiazepin-2-one (21)
