108734-36-7

Upstream product

• 108734-35-6 1-(3-Ethoxycarbonyl-propyl)-3,5-dimethoxy-cyclohexa-2,5-dienecarboxylic acid 
• 2969-81-5 Ethyl 4-bromobutyrate 
• 20469-65-2 1-bromo-3,5-dimethoxybenzene 
• 151073-69-7 (4-ethoxy-4-oxobutyl)zinc(II) bromide 
• 7425-53-8 ethyl 4-iodobutyrate 
• 89981-17-9 3,5-dimethoxy-1-phenylmagnesium chloride 

Downstream Products

• 108734-37-8 4-(2-Formyl-3,5-dimethoxy-phenyl)-butyric acid ethyl ester 
• 591247-09-5 1-(4'-hydroxycarbonylphenyl)-4-(3'',5''-dimethoxyphenyl)butan-1-one 
• 591247-24-4 4-(3',5'-dimethoxyphenyl)butyraldehyde 

Relevant academic research and scientific papers

Mechanochemical Activation of Zinc and Application to Negishi Cross-Coupling

A form independent activation of zinc, concomitant generation of organozinc species and engagement in a Negishi cross-coupling reaction via mechanochemical methods is reported. The reported method exhibits a broad substrate scope for both C(sp3)–C(sp2) and C(sp2)–C(sp2) couplings and is tolerant to many important functional groups. The method may offer broad reaching opportunities for the in situ generation organometallic compounds from base metals and their concomitant engagement in synthetic reactions via mechanochemical methods.

Origin of selectivity in the antibody 20F10-catalyzed Yang cyclization

The first antibody-catalyzed Yang (Norrish type II) cyclization has been achieved with antibodies that were elicited against cis- and trans-2,3-diaryloxetanes. The photocyclization of 1,4-diarylbutan-1-one produced a single stereoisomer of cis-1,2-diarylc

SYNTHETIC STUDIES OF RABDOSIA DITERPENE LACTONES I: THE PREPARATION OF A KEY TRICYCLIC INTERMEDIATE

A strategy is proposed for the synthesis of Rabdosia diterpene lactones, eg. effusin 2 and the preparation of a suitable tricyclic intermediate 6 described.