1087345-31-0

Basic information

• Product Name: (R)-BendrofluMethiazide
• Synonyms: (R)-BendrofluMethiazide;(3R)-3,4-Dihydro-3-(phenylMethyl)-6-(trifluoroMethyl)-2H-1,2,4-benzothiadiazine-7-sulfonaMide 1,1-Dioxide
• CAS NO: 1087345-31-0
• Molecular Formula: C₁₅H₁₄F₃N₃O₄S₂
• Molecular Weight: 421.4145696
• Product Categories: Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 1087345-31-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-BendrofluMethiazide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-BendrofluMethiazide(1087345-31-0)
• EPA Substance Registry System: (R)-BendrofluMethiazide(1087345-31-0)

Safety Data

• Hazardous Substances Data: 1087345-31-0(Hazardous Substances Data)

Usage

Uses

The R-enatiomer of the diuretic Bendroflumethiazide (B133500).

Upstream product

• 73-48-3 bendroflumethiazide 
• 654-62-6 4-amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide 
• 122-78-1 phenylacetaldehyde 

Relevant articles and documents

Uridine, thymidine and inosine used as chiral stationary phases in HPLC

In this paper, we present the first enantioseparations research using thymidine, uridine and inosine as chiral stationary phase bonded to silica gel via 3-(triethoxysilyl)propyl isocyanate in HPLC. Thymidine and uridine chiral stationary phases possess enantioseparation selectivity for alcohols, amines, ketones and carboxylic acids to some degree in normal-phase and reversed-phase mode. This work indicates that nucleoside or deoxynucleoside can be useful for the separation of enantiomers in the liquid phase as a new kind of chiral stationary phase.

COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS

The present invention relates to derivatized cyclofructan compounds, compositions comprising derivatized cyclofructan compounds, and methods of using compositions comprising derivatized cyclofructan compounds for chromatographic separations of chemical species, including enantiomers. Said compositions may comprise a solid support and/or polymers comprising derivatized cyclofructan compounds.

Direct catalytic asymmetric synthesis of cyclic aminals from aldehydes

A highly enantioselective Bronsted acid catalyzed direct synthesis of cyclic aminals from aldehydes has been developed. The methodology has been applied to the first asymmetric synthesis of several antihypertensive aminal drugs including (R)-Thiabutazide. Copyright