1087654-13-4Relevant academic research and scientific papers
A concise synthesis of benzo[h]- and pyrido[3,2-h]-δ-carbolin-2,4- diones from one-pot reaction of β-lactam carbenes with naphthyl and quinolyl isonitriles
Shi, Gao-Feng,Kang, Zhi-Mei,Jiang, Xiao-Ping,Cheng, Ying
, p. 2883 - 2890 (2008)
The one-pot reaction of β-lactam carbenes with 1-naphthyl or 5-quinolyl isonitriles followed by treatment with aqueous hydrochloride produced benzo[h]-δ-carbolin-2,4-diones or pyrido[3,2-h]-δ-carbolin-2,4- diones, respectively, in moderate yields. The easy availability of β-lactam carbenes and aryl isonitriles, and the simple chemical manipulations render our approach practical in the synthesis of various novel aryl fused δ-carboline derivatives, which are not easily prepared by other synthetic methods. Georg Thieme Verlag Stuttgart.
