1087798-38-6 Usage
General Description
6-(Boc-amino)spiro[3.3]heptane-2-carboxylic acid is a chemical compound that is commonly used in the field of organic synthesis. It is a spirolactam derivative that contains a Boc (tert-butyloxycarbonyl) protected amino group, which makes it a valuable building block for the synthesis of various pharmaceuticals and bioactive compounds. The spiro[3.3]heptane core in this compound provides unique structural and conformational properties that make it suitable for drug discovery and development. Additionally, the presence of a carboxylic acid moiety in this compound allows for further derivatization and modification to tailor its properties for specific applications in medicinal chemistry. Overall, 6-(Boc-amino)spiro[3.3]heptane-2-carboxylic acid is a versatile chemical intermediate with potential applications in pharmaceutical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 1087798-38-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,7,7,9 and 8 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1087798-38:
(9*1)+(8*0)+(7*8)+(6*7)+(5*7)+(4*9)+(3*8)+(2*3)+(1*8)=216
216 % 10 = 6
So 1087798-38-6 is a valid CAS Registry Number.
1087798-38-6Relevant articles and documents
Cyclobutane-derived diamines: Synthesis and molecular structure
Radchenko, Dmytro S.,Pavlenko, Sergiy O.,Grygorenko, Oleksandr O.,Volochnyuk, Dmitriy M.,Shishkina, Svitlana V.,Shishkin, Oleg V.,Komarov, Igor V.
experimental part, p. 5941 - 5952 (2010/11/04)
Cyclobutane diamines (i.e., cis- and trans-1,3-diaminocyclobutane, 6-amino-3-azaspiro[3.3]heptane, and 3,6-diaminospiro[3.3]heptane) are considered as promising sterically constrained diamine building blocks for drug discovery. An approach to the syntheses of their Boc-monoprotected derivatives has been developed aimed at the preparation of multigram amounts of the compounds. These novel synthetic schemes exploit classical malonate alkylation chemistry for the construction of cyclobutane rings. The conformational preferences of the cyclobutane diamine derivatives have been evaluated by X-ray diffraction and compared with the literature data on sterically constrained diamines, which are among the constituents of commercially available drugs.