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Thiophosphoric acid O-[(2R,3S,5R)-5-(6-amino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-ylmethyl] ester O'-{(2R,3S,5R)-5-(6-amino-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl} ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

108782-87-2

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108782-87-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 108782-87-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,7,8 and 2 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 108782-87:
(8*1)+(7*0)+(6*8)+(5*7)+(4*8)+(3*2)+(2*8)+(1*7)=152
152 % 10 = 2
So 108782-87-2 is a valid CAS Registry Number.

108782-87-2Downstream Products

108782-87-2Relevant academic research and scientific papers

STUDIES ON STEREOSSPECIFIC FORMATION OF P-CHIRAL INTERNUCLEOTIDE LINKAGE. SYNTHESIS OF DIASTEREOISOMERIC 2'-DEOXYADENYLYL S-METHYLPHOSPHOROTHIOATES VIA NUCLEOSIDE HYDROXYL ACTEVATION

Lesnikowski, Zbigniew J.,Sibinska, Anna

, p. 5025 - 5034 (1986)

Substitution of 4-nitrophenoxy group at phosphorus atom of 5'-O-monomethoxytrityl-2'-deoxyadenosine 3'-O- (4) by base-activated 5'-hydroxyl function of 3'-O-tert-butyldimethylsilyl-2'-deoxyadenosine (5)gives fully protected P-chiral 2'-deoxyadenylyl(3',5') 2'-deoxyadenosine S-methylphosphorothioates (6), .Demethylation of internucleotideS-methylphosphorothioate group in 6 and deprotection of 3'-and 5'-hydroxyl functions lead to diastereoisomeric mixture of 2'-deoxyadenylyl(3',5')2'-deoxyadenosine-O,O-phosphorothioates (7).

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