1088-92-2 Usage
Uses
Used in Pharmaceutical Industry:
Nifurtoinol is used as an antimicrobial agent for its broad-spectrum activity against various pathogens, including bacteria, fungi, and viruses. Its unique chemical structure allows it to disrupt the cell membrane and inhibit essential cellular processes, leading to the death of the pathogen.
Used in Agriculture:
In the agricultural sector, nifurtoinol is used as a fungicide to protect crops from fungal infections. Its ability to target a wide range of fungi makes it an effective tool in managing plant diseases and ensuring a healthy harvest.
Used in Environmental Applications:
Nifurtoinol can be employed as a biocide in water treatment and industrial processes to control microbial growth and prevent biofouling. Its effectiveness in controlling various microorganisms makes it a valuable asset in maintaining clean and efficient systems.
Used in Cosmetics:
In the cosmetics industry, nifurtoinol is used as a preservative to prevent microbial contamination and extend the shelf life of products. Its broad-spectrum antimicrobial activity ensures the safety and stability of cosmetic formulations.
Used in Research:
Nifurtoinol is also used in scientific research as a tool to study the mechanisms of action of various pathogens and to develop new strategies for combating infectious diseases. Its unique chemical properties make it an interesting compound for exploring novel therapeutic approaches.
Originator
Urfadyne,Zambon,W. Germany,1969
Manufacturing Process
Three liters of 5% formaldehyde solution (2,625 cc water and 375 cc 40%
formalin) containing 50 g of nitrofurantoin is refluxed for about 5 minutes,
then filtered hot and cooled. The crystallized product is filtered and washed
with 1% formaldehyde solution. It is air dried and then further dried at 65°C.
There is obtained 33 g of 3-hydroxymethyl-1-(5-nitrofurfurylideneamino)
hydantoin.
Therapeutic Function
Antibacterial
Pharmaceutical Applications
The hydroxymethyl derivative of nitrofurantoin, formulated
for oral administration. The activity is similar to that of nitrofurantoin.
Little is known about the pharmacokinetic behavior.
It is said to be more rapidly absorbed than nitrofurantoin
and excreted into the urine to a greater extent. Available in
some countries in continental Europe.
Check Digit Verification of cas no
The CAS Registry Mumber 1088-92-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,8 and 8 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1088-92:
(6*1)+(5*0)+(4*8)+(3*8)+(2*9)+(1*2)=82
82 % 10 = 2
So 1088-92-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N4O6/c14-5-11-7(15)4-12(9(11)16)10-3-6-1-2-8(19-6)13(17)18/h1-3,14H,4-5H2/b10-3+
