1088111-07-2Relevant academic research and scientific papers
An organocatalytic approach to the construction of chiral oxazolidinone rings and application in the synthesis of antibiotic linezolid and its analogues
Song, Lirong,Chen, Xiaobei,Zhang, Shilei,Zhang, Haoyi,Li, Ping,Luo, Guangshun,Liu, Wenjing,Duan, Wenhu,Wang, Wei
supporting information; experimental part, p. 5489 - 5492 (2009/06/06)
(Chemical Equation Presented) An efficient, catalytic asymmetric approach to antibacterial agent linezolid has been developed. The route features organocatalytic, highly enantioselective aldol and Beckman rearrangement reactions. The strategy has also bee
