1088239-18-2Relevant academic research and scientific papers
α-Ketiminophosphonates: Synthesis and applications
Vicario, Javier,Aparicio, Domitila,Palacios, Francisco
, p. 638 - 643 (2011/06/22)
The synthesis of α-iminophosphonates derived from ketones has been achieved by aza-Wittig reaction of P-trimethylphosphazenes with acylphosphonates. These unstable compounds can be used for the synthesis of chiral α-aminophosphonate derivatives through ad
Conjugate addition of amines to an α,β-unsaturated imine derived from α-aminophosphonate. Synthesis of γ-amino-α- dehydroaminophosphonates
Vicario, Javier,Aparicio, Domitila,Palacios, Francisco
supporting information; experimental part, p. 452 - 455 (2009/04/07)
(Chemical Equation Presented) Aza-Michael reaction of ammonia, aliphatic, aromatic and optically active amines to an α,β-unsaturated imine derived from α-aminophosphonate affords α-dehydroaminophosphonates with a γ-stereogenic center bearing an amino group. Resulting γ-amino α-dehydroaminophosphonates can be used for the preparation of phosphorylated pyrimidine derivatives.
