108836-46-0Relevant articles and documents
Structure-Activity Relationships in an Imidazole-Based Series of Thromboxane Synthase Inhibitors
Manley, Paul W.,Allanson, Nigel M.,Booth, Robert F. G.,Buckle, Philip E.,Kuzniar, Edward J.,et al.
, p. 1588 - 1595 (2007/10/02)
Analogues of 4-methyl>ethoxy>methyl>benzoic acid (5m) were prepared and evaluated as thromboxane synthase inhibitors.A series of esters of 5m showed a parabolic relationship between lipophilicity and inh