108840-32-0Relevant academic research and scientific papers
Synthesis, biological evaluation and modeling studies of terphenyl topoisomerase II α inhibitors as anticancer agents
Qiu, Jin,Zhao, Baobing,Zhong, Wanxia,Shen, Yuemao,Lin, Houwen
, p. 427 - 435 (2015)
We report the synthesis and evaluation of a series of novel terphenyls. Compound 17 had the most potent anticancer activity, indicating that the phenolic hydroxyl was a key group. A DNA relaxation test showed that compound 17 had a strong inhibitory effec
