108858-86-2

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(4-Aminophenyl)cyclopropanecarbonitrile is used as a key intermediate for the synthesis of various pharmaceutical drugs. Its unique structure and reactivity allow for the creation of a wide range of heterocyclic compounds, which are essential in the development of new medications.
Used in Organic Chemistry Research:
APC is utilized as a valuable reagent in organic chemistry research, where its stable nature and potential for various synthetic applications make it an ideal candidate for studying and developing new chemical reactions and processes.
Used in the Preparation of Heterocyclic Compounds:
1-(4-Aminophenyl)cyclopropanecarbonitrile is used as a versatile building block for the preparation of various heterocyclic compounds, which are crucial in the field of pharmaceuticals and organic chemistry. Its unique structure and reactivity contribute to the development of novel compounds with potential applications in different industries.

Upstream product

• 555-21-5 4-Nitrophenylacetonitrile 
• 935-44-4 1-cyano-1-phenylcyclopropane 
• 50685-26-2 4-(cyanomethyl)benzoic acid 
• 915020-91-6 4-(1-cyanocyclopropyl)benzoic acid 
• 408328-42-7 1-(4-nitrophenyl)-1-cyclopropylcarbonitrile 

Downstream Products

• 954135-62-7 1-(4-amino-3-bromo-phenyl)-cyclopropanecarbonitrile 

Relevant academic research and scientific papers

COMPOUNDS FOR TREATING AND PREVENTING GROWTH HORMONE RECEPTOR-DEPENDENT CONDITIONS

The invention relates to compounds, in particular pyrimidine-2,4-diamines, analogues and salts thereof and pharmaceutical compositions comprising pyrimidine-2,4-diamines analogues and salts thereof for use in the treatment and prevention of a disease, in particular a growth hormone receptor-dependent condition. The invention also relates to methods of using these compounds and compositions to treat physiological dsorders related to the amount or activity of growth hormone. In a particular embodiment, the invention relates to a compound according to formula 1 for use in the treatment or prevention of a disease in a subject

ROR-GAMMA MODULATORS AND USES THEREOF

The present invention relates to a compound of formula I, or an isotopic form, stereoisomer, a tautomer, a pharmaceutically acceptable salt, a solvate, a polymorph, a prodrug, N-oxide or S-oxide thereof; and processes for their preparation. The invention further relates to pharmaceutical compositions containing the compounds and their use in the treatment of diseases or disorders mediated by RORγ.

INHIBITORS OF C-FMS KINASE

The invention is directed to compounds of Formula I: wherein Z, X, J, R2 and W are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, es

IMIDAZOQUINOLINES AS LIPID KINASE INHIBITORS

The invention relates to novel organic compounds of formula (I) processes for the preparation thereof, the application thereof in a process for the treatment of the human or animal body, the use thereof - alone or in combination with one or more other pharmaceutically active compounds - for the treatment of an inflammatory or obstructive airway disease, such as asthma, disorders commonly occurring in connection with transplantation, or a proliferative disease, such as a tumor disease.