1088583-53-2

Upstream product

• 1088583-51-0 (6S)-6-[benzyl(tert-butyloxycarbonyl)amino]-5,6,7,8-tetrahydronaphthalen-1-yl trifluoromethanesulfonate 
• 844891-04-9 1,3,5-trimethylpyrazole-4-boronic acid pinacol ester 

Downstream Products

• 1044513-00-9 (2S)-benzyl-[5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-amine 

Relevant academic research and scientific papers

Heterocyclyl-substituted-tetrahydro-naphthalen derivatives as 5-HT7 receptor ligands

The present invention relates to heterocyclyl-substituted-tetrahydro-naphthalen compounds of general formula (I) and (Iprot), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans or animals, mediated by the receptor 5-HT7 affinity.

Combination of a 5-HT7 receptor ligand and an opioid receptor ligand

The present invention refers to a combination of a 5HT7 receptor ligand and an opioid recptor ligand, especially of a 5HT7 receptor agonist and an opioid recptor agonist, a medicament comprising this combination, or the use of this combination for the treatment of the symptoms of pain, the prevention or the prophylaxis of the symptoms of pain.