1088639-99-9Relevant articles and documents
Asymmetric aza-Michael reactions of α,β-unsaturated ketones with bifunctional organic catalysts
Lu, Xiaojie,Deng, Li
supporting information; experimental part, p. 7710 - 7713 (2009/04/11)
Synergy makes it possible: Bifunctional cinchona alkaloids are found to promote the first highly enantioselective organocatalytic aza-Michael reactions with α,β-unsaturated ketones. In addition to utilizing practical catalysts, readily accessible substrates, and commercially available reagents, this reaction affords a synthetically valuable scope that is complimentary to existing methods catalyzed by chiral metal complexes.