1088780-17-9Relevant academic research and scientific papers
Asymmetric synthesis of (-)-6-epi-centrolobine
Reddy, Chada Raji,Madhavi, Pasupulety Phani,Chandrasekhar, Srivari
experimental part, p. 2939 - 2942 (2009/04/07)
A stereoselective total synthesis of (-)-6-epi-centrolobine, an unnatural analogue of (-)-centrolobine, starting from readily available tri-O-acetyl-D-glucal has been described for the first time. The key steps involved in this synthetic approach are stereoselective C-glycosidation, dehydroxylation and Wittig reaction. The target molecule was achieved in nine steps with 49% overall yield. Georg Thieme Verlag Stuttgart.
