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1088884-71-2

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1088884-71-2 Usage

General Description

2,2-dimethylazetidine HCl, also known as CAS number 2199-59-9, is a chemical compound that belongs to the class of azetidines. It is a white to off-white crystalline powder that is soluble in water and organic solvents. 2,2-dimethylazetidine HCl is mainly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. As a HCl salt, it is commonly used as a reagent in organic synthesis and as a building block in the production of diverse chemical products. In addition, 2,2-dimethylazetidine HCl has potential applications in the development of new drugs, due to its unique chemical structure and properties. Overall, this chemical has various industrial and research uses, particularly in the field of organic chemistry and pharmaceutical development.

Check Digit Verification of cas no

The CAS Registry Mumber 1088884-71-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,8,8,8 and 4 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1088884-71:
(9*1)+(8*0)+(7*8)+(6*8)+(5*8)+(4*8)+(3*4)+(2*7)+(1*1)=212
212 % 10 = 2
So 1088884-71-2 is a valid CAS Registry Number.

1088884-71-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2-dimethylazetidine,hydrochloride

1.2 Other means of identification

Product number -
Other names 2,2-Dimethylazetidine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1088884-71-2 SDS

1088884-71-2Downstream Products

1088884-71-2Relevant articles and documents

Novel acetylcholine and carbamoylcholine analogues: Development of a functionally selective α4β2 nicotinic acetylcholine receptor agonist

Hansen, Camilla P.,Jensen, Anders A.,Christensen, Jeppe K.,Balle, Thomas,Liljefors, Tommy,Fr?lund, Bente

experimental part, p. 7380 - 7395 (2009/12/07)

A series of carbamoylcholine and acetylcholine analogues were synthesized and characterized pharmacologically at neuronal nicotinic acetylcholine receptors (nAChRs). Several of the compounds displayed low nanomolar binding affinities to the α4β2 nAChR and pronounced selectivity for this subtype over α3β4, α4β4, and α7 nAChRs. The high nAChR activity of carbamoylcholine analogue 5d was found to reside in its R-enantiomer, a characteristic most likely true for all other compounds in the series. Interestingly, the pronounced α4β2 selectivities exhibited by some of the compounds in the binding assays translated into functional selectivity. Compound 5a was a fairly potent partial α4β2 nAChR agonist with negligible activities at the α3β4 and α7 subtypes, thus being one of the few truly functionally selective α4β 2 nAChR agonists published to date. Ligand-protein docking experiments using homology models of the amino-terminal domains of α4β2 and α3β4 nAChRs identified residues Val111(β2)/Ile113(β4) , Phe119(β2)/Gln121(β4), and Thr155(α4)/Ser150(α3) as possible key determinants of the α4β2/α 3β4-selectivity displayed by the analogues.

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