1088907-66-7Relevant academic research and scientific papers
Copper anchored on phosphorus g-C3N4as a highly efficient photocatalyst for the synthesis ofN-arylpyridin-2-amines
Di, Jia-Qi,Zhang, Mo,Chen, Yu-Xuan,Wang, Jin-Xin,Geng, Shan-Shan,Tang, Jia-Qi,Zhang, Zhan-Hui
, p. 1041 - 1049 (2021/02/09)
A heterogeneous photocatalyst based on copper modified phosphorus doped g-C3N4(Cu/P-CN) has been prepared and characterized. This recyclable catalyst exhibited high photocatalytic activity for the synthesis ofN-arylpyridin-2-amine derivatives by the reaction of 2-aminopyridine and aryl boronic acid at room temperature under the irradiation of blue light. Importantly, the range of substrates for this coupling reaction has been expanded to include aryl boronic acids with strong electron-withdrawing groups as viable raw materials. In addition, this heterogeneous catalyst can be used at least 6 times while maintaining its catalytic activity.
PROSTACYCLIN RECEPTOR AGONIST
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Paragraph 0236-0238; 0293-0295, (2020/12/22)
A compound represented by formula (I) or an isomer or a pharmaceutically acceptable salt thereof. The present invention also relates to an application of the same in preparing a drug for treating a disease related to a PGI2 receptor.
Highly regioselective Buchwald-Hartwig amination at C-2 of 2,4-dichloropyridine enabling a novel approach to 2,4-bisanilinopyridine (BAPyd) libraries
Burton, Rebecca J.,Crowther, Mandy L.,Fazakerley, Neal M.,Fillery, Shaun M.,Hayter, Barry M.,Kettle, Jason G.,McMillan, Caroline A.,Perkins, Paula,Robins, Peter,Smith, Peter M.,Williams, Emma J.,Wrigley, Gail L.
supporting information, p. 6900 - 6904 (2019/04/10)
The highly regioselective Buchwald-Hartwig amination at C-2 of the cheap and readily accessible reagent, 2,4-dichloropyridine with a range of anilines and heterocyclic amines is described. This new methodology is robust and provides facile access to 4-chl
Identification of G protein-coupled receptor 120-selective agonists derived from PPARγ agonists
Suzuki, Takayoshi,Igari, Sou-Ichi,Hirasawa, Akira,Hata, Mie,Ishiguro, Masaji,Fujieda, Hiroki,Itoh, Yukihiro,Hirano, Tatsuya,Nakagawa, Hidehiko,Ogura, Michitaka,Makishima, Makoto,Tsujimoto, Gozoh,Miyata, Naoki
supporting information; experimental part, p. 7640 - 7644 (2009/11/30)
A weak, nonselective G protein-coupled receptor 120 (GPR 120) agonist 10 was found by screening a series of carboxylic acids derived from the peroxisome proliferator-activated receptor γ (PPARγ) agonist 3. Modification based on the homology model of GPR12
