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2-Pyridinecarboxamide, 3-hydroxy-N-(4-nitrophenyl)-, also known as 3-hydroxy-N-(4-nitrophenyl)nicotinamide, is a chemical compound with the molecular formula C12H9N3O4. It is a derivative of nicotinamide, which is a form of vitamin B3. 2-Pyridinecarboxamide, 3-hydroxy-N-(4-nitrophenyl)- features a pyridine ring with a carboxamide group at the 2-position, a hydroxyl group at the 3-position, and a 4-nitrophenyl group attached to the nitrogen atom. It is an organic compound with potential applications in pharmaceuticals and chemical research, particularly in the synthesis of various biologically active molecules. The presence of the nitro group and the hydroxyl group in the molecule can influence its reactivity and properties, making it a subject of interest for further study and development.

1089-22-1

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1089-22-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1089-22-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,8 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1089-22:
(6*1)+(5*0)+(4*8)+(3*9)+(2*2)+(1*2)=71
71 % 10 = 1
So 1089-22-1 is a valid CAS Registry Number.

1089-22-1Downstream Products

1089-22-1Relevant academic research and scientific papers

Antimycobacterial and antifungal isosters of salicylamides

Waisser, Karel,Pe?ina, Milan,Holy, Pavel,Pour, Milan,Bure?, Otakar,Kune?, Ji?í,Klime?ová, V?ra,Buchta, Vladimír,Kubanová, Petra,Kaustová, Jarmila

, p. 322 - 335 (2007/10/03)

A set of 40 derivatives of 3-hydroxypicolinic acid and 2-sulfanylbenzoic acid, isosteric to salicylanilides was synthesized. The compounds were evaluated for in vitro activity against Mycobacterium tuberculosis, Mycobacterium kansasii and Mycobacterium avium, Candida albicans, Candida tropicalis, Candida krusei, Candida glabrata, Trichosporon beigelii, Aspergillus fumigatus, Absidia corymbifera, Trichophyton mentagrophytes and Microsporum gypseum. Structure-activity relationships of antimycobacterial activity and antifungal activity against T. mentagrophytes and M. gypseum were analyzed by the Free-Wilson method. An increase in antimycobacterial activity was observed only for the sulfanylbenzoic acid derivatives, especially those with the benzyl moiety. The antifungal activity was not significant.

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