108915-04-4

Basic information

• Product Name: 2-[(4S)-4,5-dihydro-4-(1-Methylethyl)-2-oxazolyl]- yridine
• Synonyms: 2-[(4S)-4,5-dihydro-4-(1-Methylethyl)-2-oxazolyl]- yridine;(S)-2-(4-Isopropyl-4,5-dihydro-oxazol-2-yl)-pyridine;2-[(4S)-4,5-Dihydro-4-isopropyl-2-oxazolyl]pyridine;2-[(4S)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]-Pyridine;2-[(4S)-4,5-Dihydro-4-isopropyl-2-oxazolyl]pyridine,99%e.e.
• CAS NO: 108915-04-4
• Molecular Formula: C₁₁H₁₄N₂O
• Molecular Weight: 190.24166
• Mol File: 108915-04-4.mol
• Article Data: 13

Chemical Properties

• Melting Point: 53 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 110-120 °C(Press: 0.1 Torr)
• Appearance: /
• Density: 1.14±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.67±0.70(Predicted)
• CAS DataBase Reference: 2-[(4S)-4,5-dihydro-4-(1-Methylethyl)-2-oxazolyl]- yridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(4S)-4,5-dihydro-4-(1-Methylethyl)-2-oxazolyl]- yridine(108915-04-4)
• EPA Substance Registry System: 2-[(4S)-4,5-dihydro-4-(1-Methylethyl)-2-oxazolyl]- yridine(108915-04-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 108915-04-4(Hazardous Substances Data)

Usage

General Description

2-[(4S)-4,5-dihydro-4-(1-Methylethyl)-2-oxazolyl]- yridine is a chemical compound with the molecular formula C11H14N2O. It is a heterocyclic compound containing a pyridine ring and an oxazole ring. The 4S indicates the stereochemistry of the compound, with the 4-methyl group in the S (sinister, or left) configuration. 2-[(4S)-4,5-dihydro-4-(1-Methylethyl)-2-oxazolyl]- yridine is used in pharmaceutical research and may have potential applications in the development of new drugs. Its precise properties and uses are still being explored, and it is not widely known or commercially available at this time.

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Relevant articles and documents

Pyridine-oxazoline and quinoline-oxazoline ligated cobalt complexes: Synthesis, characterization, and 1,3-butadiene polymerization behaviors

A series of cobalt complexes supported by pyridine-oxazoline (Pyox) and quinoline-oxazoline (Quox) were synthesized. Determined by single crystal X-ray crystallography, complexes 6a and 7c adopted distorted octahedron and trigonal bipyramid geometries, re

Natural Kaolinitic clay catalyzed conversion of nitriles to 2-oxazolines

Natural Kaolinitic clay has been found effective as catalyst in the conversion of aromatic and aliphatic nilriles with 1,2-aminoalcohol to 2-oxazolines (56-96%, yield).

Chemoselective oxidation of polyols with chiral palladium catalysts

Chiral palladium-based catalysts derived from pyridinyl oxazoline (pyOx) ligands catalyze the oxidation of alcohols, including 1,2-diols, triols, and tetraols, with high regio- and chemoselectivity. Screening of various chiral oxazoline-derived ligands for the oxidation of a model diol, 1,2-propanediol (1,2-PD), revealed that the nature of the ligand had a significant influence on the activity and chemoselectivity for oxidation of vicinal diols. The PyOx ligands containing an α-methyl substituent were the most active for the oxidation of 1,2-PD using benzoquinone as the terminal oxidant. Oxidation of vicinal diols and polyols occurs selectively at the secondary alcohol to afford α-hydroxy ketones in isolated yields of 62-87%. Chemoselective oxidation of meso-erythritol with the chiral [(S)-(α-Me(tert-Bu)PyOx)Pd(OAc)] 2[OTf]2 afforded (S)-erthyrulose in 62% yield and 24% ee.

Parallel screening of asymmetric bidentate ligands in zinc catalyzed transfer hydrogenation

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