1089192-08-4Relevant academic research and scientific papers
Iron-catalyzed enyne cross-coupling reaction
Hatakeyama, Takuji,Yoshimoto, Yuya,Gabriel, Toma,Nakamura, Masaharu
supporting information; experimental part, p. 5341 - 5344 (2009/06/06)
(Chemical Equation Presented) In the presence of 0.5-1 mol % of FeCl 3 with lithium bromide as a crucial additive, alkynyl Grignard reagents, prepared from the corresponding alkynes and methylmagnesium bromide, react with alkenyl bromides or triflates to give the corresponding conjugated enynes in high to excellent yields. The reaction shows wide applicability to various terminal alkynes and alkenyl electrophiles.
