1089216-06-7

Upstream product

• 1089216-03-4 [2-(3-butylureido)-7-cyclohexanemethyl-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl]-acetic acid ethyl ester 

Downstream Products

• 1089216-08-9 [2-(3-butylureido)-7-cyclohexanemethyl-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl]-acetic acid 4-pentenyl ester 
• 1089216-07-8 N-(6-azidohexyl)-2-[2-(3-butylureido)-7-(cyclohexylmethyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl]ethanamide 
• 1089216-09-0 2-hydroxyethyl-2-[2-(3-butylureido)-7-(cyclohexylmethyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl]acetate 
• 1343496-04-7 2-(2-(2-(3-butylureido)-7-(cyclohexylmethyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)acetoxy)ethyl (2-(methacryloyloxy)ethyl) succinate 
• 1343496-03-6 4-(2-(2-(2-(3-butylureido)-7-(cyclohexylmethyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)acetoxy)ethoxy)-4-oxobutanoic acid 

Relevant academic research and scientific papers

Hydrogen-bonded deugdan heterocomplex: Structure and stability and a scalable synthesis of DeUG with reactive functionality

A convenient, scalable synthesis of the supramolecular building block 7-deazaguanine-based urea (DeUG) is reported. Incorporation of reactive moieties (DeUG azide 10 and alkyne 11 for copper-catalyzed azide-alkyne cycloadditions, "click chemistry") and a demonstration of transesterification (DeUG glycol, 12) highlights the versatility. X-ray structures of DeUG and a DeUG-DAN heterocomplex were obtained. Kassoc for the 1.2 heterocomplex was estimated to be 2 x 108 M-1 in chloroform.