1089274-75-8

Basic information

• Product Name: 1-BOC-3-[(2-AMINOPHENYL)AMINO]-PIPERIDINE
• Synonyms: 1-BOC-3-[(2-AMINOPHENYL)AMINO]-PIPERIDINE;Tert-butyl 3-((2-aminophenyl)amino)piperidine-1-carboxylate
• CAS NO: 1089274-75-8
• Molecular Formula: C16H25N3O2
• Molecular Weight: 291.3886
• Mol File: 1089274-75-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-BOC-3-[(2-AMINOPHENYL)AMINO]-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-3-[(2-AMINOPHENYL)AMINO]-PIPERIDINE(1089274-75-8)
• EPA Substance Registry System: 1-BOC-3-[(2-AMINOPHENYL)AMINO]-PIPERIDINE(1089274-75-8)

Safety Data

• Hazardous Substances Data: 1089274-75-8(Hazardous Substances Data)

Usage

General Description

1-BOC-3-[(2-aminophenyl)amino]-piperidine is a chemical compound that belongs to the piperidine class. It has a BOC (tert-butyloxycarbonyl) protecting group attached to the nitrogen atom, which is commonly used in organic synthesis to protect amines from unwanted reactions. The compound also contains an amino group attached to a phenyl group, making it potentially useful in medicinal chemistry and drug development. The piperidine ring structure of the compound is a common motif found in many biologically active molecules and pharmaceuticals. Overall, 1-BOC-3-[(2-aminophenyl)amino]-piperidine has potential applications in organic synthesis, drug discovery, and medicinal chemistry research.

Upstream product

• 360555-54-0 (R)-3-(2-nitrophenylamino)piperidine-1-carboxylic acid tert-butyl ester 
• 188111-79-7 tert-butyl (3R)3-aminopiperidine-1-carboxylate 
• 1493-27-2 ortho-nitrofluorobenzene 
• 625471-18-3 tert-butyl (3S)-3-aminopiperidine-1-carboxylate 
• 88-73-3 2-Chloronitrobenzene 
• 1304778-21-9 C₁₆H₂₃N₃O₄ 
• 144243-24-3 tert‐butyl 3‐aminopiperidine‐1‐carboxylate 

Downstream Products

• 1575821-06-5 tert-butyl 3-(2-(4-chlorobenzamido)-1H-benzo[d]imidazol-1-yl)piperidine-1-carboxylate 
• 1575819-19-0 4-chloro-N-(1-(piperidin-3-yl)-1H-benzo[d]imidazol-2-yl)benzamide hydrochloride 
• 1575819-20-3 4-chloro-N-(1-(1-(2-cyanoacetyl)piperidin-3-yl)-1H-benzo[d]imidazol-2-yl)benzamide 
• 1575817-35-4 4-chloro-N-(1-(1-(2-cyano-4-methylpent-2-enoyl)piperidin-3-yl)-1H-benzo[d]imidazol-2-yl)benzamide 
• 1575817-36-5 N-(1-(1-acryloylpiperidin-3-yl)-1H-benzo[d]imidazol-2-yl)-4-chlorobenzamide 
• 1089274-87-2 (S)-2-(dibenzylamino)propyl 3-(1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)piperidine-1-carboxylate 

Relevant articles and documents

BENZIMIDAZOLE DERIVATIVES AS RLK and ITK INHIBITORS

The present disclosure is directed to certain inhibitors of RLK and ITK of formula (I), pharmaceutical compositions comprising such compounds, and method of treating diseases mediated by inhibition of RLK and ITK.

HETEROCYCLIC COMPOUNDS AND METHODS OF USE

Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans

The Invention relates to compounds having an antiparasitic activity, and to their use as a drug, in particular as a drug for the prevention and/or treatment of parasitic diseases caused by apicomplexans. The invention also relates to pharmaceutical compositions containing those compounds.