1089278-92-1

Basic information

• Product Name: N-(2,6-difluorophenyl)-3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
• Synonyms: N-(2,6-difluorophenyl)-3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
• CAS NO: 1089278-92-1
• Molecular Weight: 605.647
• Mol File: 1089278-92-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2,6-difluorophenyl)-3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,6-difluorophenyl)-3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide(1089278-92-1)
• EPA Substance Registry System: N-(2,6-difluorophenyl)-3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide(1089278-92-1)

Safety Data

• Hazardous Substances Data: 1089278-92-1(Hazardous Substances Data)

Upstream product

• 1089278-45-4 3-[3-(2-chloro-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-benzamide 
• 181513-08-6 3-(2-(dimethylamino)ethoxy)benzenamine 
• 1089278-93-2 3-(2-(dimethylamino)ethoxy)benzenamine hydrochloride 

Relevant articles and documents

Discovery and optimization of imidazo[1,2-a]pyridine inhibitors of insulin-like growth factor-1 receptor (IGF-1R)

The optimization of imidazo[1,2-a]pyridine inhibitors as potent and selective inhibitors of IGF-1R is presented. Further optimization of oral exposure in mice is also discussed. Detailed selectivity, in vitro activity, and in vivo PK profiles of an optimi