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Taprostene is a stable prostacyclin (PGI2) analog and agonist of the prostacyclin receptor, IP. It does not activate the PGE2 receptor EP4, which, like IP, promotes vascular smooth muscle relaxation when stimulated. Taprostene has been used extensively to study the role of the IP receptor in tissue preparations and in vivo. It has also been used in the screening and evaluation of potential IP antagonists.

108945-35-3

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108945-35-3 Usage

Uses

Used in Pharmaceutical Research:
Taprostene is used as a research compound for studying the role of the prostacyclin receptor, IP, in various tissue preparations and in vivo. It helps in understanding the receptor's function and its potential as a therapeutic target.
Used in Drug Development:
Taprostene is used as a reference compound in the screening and evaluation of potential IP antagonists. This application aids in the development of new drugs targeting the IP receptor for various therapeutic purposes.
Used in Smooth Muscle Relaxation Studies:
Taprostene is used as a stable prostacyclin analog for investigating the effects of prostacyclin receptor activation on vascular smooth muscle relaxation. This application is crucial for understanding the underlying mechanisms of vascular diseases and potential treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 108945-35-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,9,4 and 5 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 108945-35:
(8*1)+(7*0)+(6*8)+(5*9)+(4*4)+(3*5)+(2*3)+(1*5)=143
143 % 10 = 3
So 108945-35-3 is a valid CAS Registry Number.
InChI:InChI=1/C24H30O5/c25-21(16-6-2-1-3-7-16)10-9-19-20-13-18(29-23(20)14-22(19)26)12-15-5-4-8-17(11-15)24(27)28/h4-5,8-12,16,19-23,25-26H,1-3,6-7,13-14H2,(H,27,28)/b10-9+,18-12-/t19-,20-,21-,22-,23+/m1/s1

108945-35-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Taprostene

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:108945-35-3 SDS

108945-35-3Upstream product

108945-35-3Downstream Products

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