108975-00-4Relevant academic research and scientific papers
Olefin Acylation Reactions on Sesquiterpene Lactones
Kalsi, P. S.,Chhina, Kiranjot
, p. 11 - 14 (2007/10/02)
The olefin acylation of a variety of sesquiterpene lactones with acetic anhydride in the presence of zinc chloride as a catalyst in methylene chloride affords β,γ-unsaturated ketones of any α,β-isomers.The 1,5-cyclodecadiene system present in constunolide (XII) undergoes cyclization followed by acylation and in 11-spirocyclopropyl system cleavage of the cyclopropane occurs.
