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109-11-5

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Product FOB Price Min.Order Supply Ability Supplier
Factory price 3-Morpholinone
Cas No: 109-11-5
USD $ 1.0-5.0 / Metric Ton 10 Metric Ton 10000 Metric Ton/Day Hebei Huanhao Biotechnology Co.,Ltd Contact Supplier
3-Ketomorpholine
Cas No: 109-11-5
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
3-Ketomorpholine
Cas No: 109-11-5
No Data 1 Kilogram 20 Metric Ton/Month Henan Allgreen Chemical Co.,Ltd Contact Supplier
High quality 3-Ketomorpholine? supplier in China
Cas No: 109-11-5
No Data No Data No Data Simagchem Corporation Contact Supplier
Morpholin-3-one
Cas No: 109-11-5
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
Morpholin-3-one
Cas No: 109-11-5
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
Morpholin-3-one
Cas No: 109-11-5
USD $ 5.0-5.0 / Kilogram 1 Kilogram 1000 Kilogram/Month Enke Pharma-tech Co.,Ltd. (Cangzhou, China ) Contact Supplier
3-Ketomorpholine
Cas No: 109-11-5
No Data 1 Kilogram 100 Kilogram/Month HENAN SUNLAKE ENTERPRISE CORPORATION Contact Supplier
Factory supply high purity morpholin-3-one in stock
Cas No: 109-11-5
No Data 1 Kilogram 1000 Kilogram/Month Shaanxi Mingqi Chemical Co., Ltd Contact Supplier
morpholin-3-one
Cas No: 109-11-5
No Data 1 Kilogram 1 Metric Ton/Month Henan Tianfu Chemical Co., Ltd. Contact Supplier

109-11-5 Usage

Description

3-ketomorpholine is also known as morpholin-3-one. It is useful pharmacological intermediate. Recent studies have shown that some morpholin-3-one derivatives could effectively cause cell cycle arrest at G1 phase, increase the levels of P53 and Fas, and induce A549 cell apoptosis in lung cancer. This indicates it might be a useful tool for elucidating the molecular mechanism of lung cancer cell apoptosis and might also be potential anti-cancer drugs. Some of its derivatives have been proven to be useful for the prevention and treatment of arteriosclerosis and hypertriglyceridemia.

References

He, Q., et al. "Novel morpholin-3-one derivatives induced apoptosis and elevated the level of P53 and Fas in A549 lung cancer cells." Bioorganic & Medicinal Chemistry 15.11(2007): 3889.
Murai, Hiromu, et al. "Morpholinone derivatives and method of use." US, US4237132. 1980.
Gonzalez-garcia, Maria Rosario, and Fernandez, Maria Carmen. "Morpholinyl derivatives useful as MOGAT-2 inhibitors." (2015).
InChI:InChI=1/C4H7NO2/c6-4-3-7-2-1-5-4/h1-3H2,(H,5,6)

109-11-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Morpholinone

1.2 Other means of identification

Product number -
Other names morpholin-3-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:109-11-5 SDS

109-11-5Related news

Novel morpholin-3-one (cas 109-11-5) derivatives induced apoptosis and elevated the level of P53 and Fas in A549 lung cancer cells08/19/2019

Previously, we found that nine kinds of new morpholin-3-one derivatives could inhibit the growth of A549 lung cancer cells in a dose-dependent manner, but how they performed their function remained unknown. In this paper, we studied the effects of the three more effective morpholin-3-one derivat...detailed

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