109075-01-6

Upstream product

• 109075-00-5 1,2,5,6-tetradeoxy-1-methyl-2-(N-benzylamino)-3,4-O-(1-methylethylidene)-5,6-(N-benzylimino)-L-iditol 
• 109074-99-9 (2S,3R,4R,5S) 1,2:5,6-N-benzyldiimino-3,4-O-isopropylidenehexanediol 

Relevant academic research and scientific papers

Nucleophilic Opening of Chiral Bis(aziridines): A Route to Enantiomerically Pure α-Amino Aldehydes or Acids and Polysubstituted Piperidines

α-Amino aldehydes or acids can be obtained by nucleophilic opening of suitably protected chiral bis(aziridines) derived from D-mannitol.Nucleophiles consist of a wide range of organometallic and heteronucleophilic reagents.Reaction orientation toward bis-

DIASTEREOSPECIFIC SYNTHESIS OF DIAZIRIDINES FROM D-MANNITOL. ACCESS TO CHIRAL α-AMINOACIDS.

Nucleophilic opening of chiral diastereoisomeric diaziridines obtained from D-mannitol leads to precursors of D or L α-aminoacids (or aldehydes) and also provides a means of synthesizing polyhydroxylated piperidines.