109086-16-0

Basic information

• Product Name: (R)-4-METHYLTHIOMANDELIC ACID
• Synonyms: (R)-4-METHYLTHIOMANDELIC ACID
• CAS NO: 109086-16-0
• Molecular Formula: C₉H₁₀O₃S
• Molecular Weight: 182.2395
• Mol File: 109086-16-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-4-METHYLTHIOMANDELIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-METHYLTHIOMANDELIC ACID(109086-16-0)
• EPA Substance Registry System: (R)-4-METHYLTHIOMANDELIC ACID(109086-16-0)

Safety Data

• Hazardous Substances Data: 109086-16-0(Hazardous Substances Data)

Usage

General Description

The chemical (R)-4-methylthiomaandelic acid is an organic compound with a molecular formula of C9H10O3S. It is a derivative of mandelic acid containing a methylthio group at the 4-position of the phenyl ring. This chemical is a chiral compound, meaning it exists in two mirror-image forms, and the (R)-enantiomer is specifically referred to as (R)-4-methylthiomaandelic acid. It is used as a chiral starting material in organic synthesis, particularly in the creation of pharmaceuticals and agrochemicals. (R)-4-METHYLTHIOMANDELIC ACID has also been studied for its potential biological activities, including antioxidant and antifungal properties.

Upstream product

• 75-25-2 Bromoform 
• 3446-89-7 4-(Methylthio)benzaldehyde 

Downstream Products

• 125330-79-2 1-[2-hydroxy-2-(4-methylthiophenyl)]ethanoyl-2-phenylpyrrolidine 
• 917905-15-8 1-[2-(3-bromo-phenyl)-pyrrolidin-1-yl]-2-hydroxy-2-(4-methylsulfanyl-phenyl)-ethanone 
• 917905-08-9 1-[2-(4-bromo-phenyl)-pyrrolidin-1-yl]-2-hydroxy-2-(4-methylsulfanyl-phenyl)-ethanone 
• 917904-17-7 2-hydroxy-1-[2-(3-methoxy-phenyl)-pyrrolidin-1-yl]-2-(4-methylsulfanyl-phenyl)-ethanone 
• 129540-05-2 (6R,10bR)-7,9-Dimethoxy-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline 
• 129540-05-2 (6R,10bS)-7,9-Dimethoxy-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline 
• 129540-06-3 (6S,10bS)-10-Methyl-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline 
• 129540-06-3 (6R,10bS)-10-Methyl-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline 
• 129540-04-1 (6R,10bR)-8-Chloro-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline 
• 129540-04-1 (6R,10bS)-8-Chloro-6-(4-methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline 
• 90390-64-0 cis-1,2,3,5,6,10b-hexahydro-6-<4-(methylthio)phenyl>pyrrolo<2,1-a>isoquinoline 
• 90390-64-0 trans-1,2,3,5,6,10b-hexahydro-6-<4-(methylthio)phenyl>pyrrolo<2,1-a>isoquinoline 
• 370102-66-2 6-(4-(methylthio)phenyl)-2,3,6,10b-tetrahydropyrrolo[2,1-a]isoquinolin-5(1H)-one 
• 129540-28-9 1-[2-(2-Chloro-phenyl)-pyrrolidin-1-yl]-2-hydroxy-2-(4-methylsulfanyl-phenyl)-ethanone 

Relevant articles and documents

The structure of McN-5652

The configuration of the diastereoisomers of 6-(4-methylthiophenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline 1 (McN-5652) is determined and unequivocally assigned by NMR spectroscopy (NOE measurements) and an X-ray structural analysis of the trans diastereoisomer. The enantiomers of cis-1 are separated by preparative HPLC on a chiral phase. One of the enantiomers of cis-1 represents the precursor for imaging the serotonin 5-HT transporter with positron emission tomography (PET).