109093-00-7

Upstream product

• 6966-03-6 2-allyl-2,2-diphenylacetic acid 
• 31469-27-9 C₂₀H₂₈O₂Si₂ 

Downstream Products

• 137415-94-2 4,5-dihydro-3,3-diphenyl-5-<<<(trifluoromethyl)sulfonyl>oxy>methyl>-2(3H)-furanone 
• 144042-73-9 4,5-dihydro-3,3-diphenyl-5-<<(methylsulfonyl)oxy>methyl>-2(3H)-furanone 
• 26327-48-0 5-methyl-3,3-diphenyl-3H-furan-2-one 
• 83160-36-5 5-(bromomethyl)-4,5-dihydro-3,3-diphenyl-2(3H)-furanone 
• 54170-88-6 5-dimethylaminomethyl-3,3-diphenyl-dihydro-furan-2-one 
• 144041-74-7 5-diethylaminomethyl-3,3-diphenyl-dihydro-furan-2-one 
• 144041-80-5 5-morpholinomethyl-3,3-diphenyl-dihydro-furan-2-one 
• 137415-99-7 5-methylene-3,3-diphenyldihydrofuran-2(3H)-one 
• 138679-47-7 dihydro-3,3-diphenyl-5-(1H-pyrazol-1-ylmethyl)-2(3H)-furanone 
• 138679-48-8 dihydro-5-[3-methyl-1H-pyrazol-1-ylmethyl]-3,3-diphenyl-2(3H)-furanone 
• 138679-49-9 dihydro-5-[(4-methyl-1H-pyrazol-1-yl)methyl]-3,3-diphenyl-2(3H)-furanone 
• 144042-18-2 4,5-dihydro-3,3-diphenyl-5-<(2-formyl-1-imidazolyl)-methyl>-2(3H)-furanone 

Relevant academic research and scientific papers

Aminolactonization of Unactivated Alkenes Catalyzed by Aryl Iodine

A one-step protocol of the aryl iodine-catalyzed aminolactonization of unactivated alkenes under oxidation conditions was first reported to efficiently construct diverse amino lactones in a short time using HNTs2 as the compatible nitrogen source. In addi

Transition-metal catalyzed synthesis of δ-hydroxy-γ-lactones from bis(trimethylsilyl) ketene acetals and allylic acetates via γ-unsaturated carboxylic acids. Comments on the formation of α-cyclopropyl carboxylic acids

Bis(trimethylsilyl)ketene acetals react with allylic acetates in the presence of Pd(0) complexes to give γ-unsaturated carboxylic acids together with α-cyclopropyl carboxylic acids. The unsaturated acids can be converted catalytically to δ-hydroxy-yγ-lactones by the H2O2/MTO system (methyltrioxorhenium) and to butenolides by Pd(II) catalyzed intramolecular cyclization reactions. The structure of two of these lactones has been established by X-ray analysis. The mechanism of the formation of the cyclopropanic acids will be discussed.

5-(1-(IMIDAZOL)METHYL)-3,3-DISUBSTITUTED-2(3H)FURANONE DERIVATIVES

Furanone compounds and compositions having anticholinergic activity are described. The compounds have the formula: STR1 wherein: the dashed line indicates either the 4,5-unsaturated or the 4,5-dihydrofuranone ring;R 1 and R 2 may be the same or different and are hydrogen, thienyl, furanyl, or cycloalkyl (C. sub.3-C 6), benzyl, phenyl, substituted phenyl or substituted benzyl wherein the phenyl or benzyl group may be substituted with halogen, trifluoromethyl, lower alkyl, lower alkoxy or hydroxy;R. sub.3, R 4 and R 5 may be the same or different and are hydrogen, lower alkyl, lower alkyl substituted with a halogen, alkoxy, amino or carboxylic acid group, an alkyl or alkylene bridge between R 4 and R. sub.5 or R 3 and the ring N, trifluoromethyl, nitro, a cycloalkyl group containing 3 to 6 carbons, halogen, benzyl, phenyl, substituted phenyl or substituted benzyl, for which the substituents are the same as those set forth for R 1 and R 2 substituted benzyl or phenyl.R 6 in the dihydrofuranone series is hydrogen or lower alkyl.Also described are the pharmaceutically acceptable quaternary alkyl and acid addition salts of such compounds. The compounds are particularly useful in the treatment of neurogenic bladder disorder and chronic obstructive pulmonary diseases.