109100-98-3Relevant academic research and scientific papers
Phosphovanadomolybdic acid catalyzed desulfurization-oxygenation of secondary and tertiary thioamides into amides using molecular oxygen as the terminal oxidant
Xu, Ning,Jin, Xiongjie,Suzuki, Kosuke,Yamaguchi, Kazuya,Mizuno, Noritaka
, p. 4865 - 4869 (2016)
In the presence of phosphovanadomolybdic acids, e.g., H6PV3Mo9O40, desulfurization-oxygenation of various kinds of structurally diverse secondary and tertiary thioamides proceeded efficiently using molecular oxygen as the terminal oxidant, affording the corresponding amides in moderate to excellent yields. In addition, 18O-labeled amides could readily be synthesized using H218O as the oxygen source.
Pd-Catalyzed Oxidation of Aldimines to Amides
Gao, Shanshan,Ma, Yaorui,Chen, Weidong,Luo, Junfei
supporting information, p. 2191 - 2194 (2018/10/02)
Methods for the synthesis of amides via the direct oxidation of imines are rarely reported. Here we report an efficient method for Pd-catalyzed oxidation of imines to amide derivatives by the use of cheap aqueous tert -butyl hydroperoxide as an oxidant through a Wacker-type reaction. This method is practically convenient and displays high functional group tolerance, allowing a variety of imines to transform into the corresponding amide derivatives in moderate to good yields.
Hypervalent Iodine-Mediated Oxidative Rearrangement of N-H Ketimines: An Umpolung Approach to Amides
Zhao, Zhenguang,Peng, Zhiyuan,Zhao, Yongli,Liu, Hao,Li, Chongnan,Zhao, Junfeng
supporting information, p. 11848 - 11853 (2017/11/28)
An umpolung approach to amides via hypervalent iodine-mediated oxidative rearrangement of N-H ketimines under mild reaction conditions is described. This strategy provides target amides with excellent selectivity in good yields. In addition, preliminary m
Iron-catalyzed C-H and C-C bond cleavage: A direct approach to amides from simple hydrocarbons
Qin, Chong,Zhou, Wang,Chen, Feng,Ou, Yang,Jiao, Ning
supporting information; experimental part, p. 12595 - 12599 (2012/01/15)
Something functional: The title reaction proceeds in the presence of azide and water to deliver amides in high yields, and it can be used in a ring-expansion strategy to generate lactams. A mechanism is proposed based on experimental results. This reaction offers a new approach to functionalizing simple and readily available hydrocarbons. DDQ=2,3-dichloro-5,6-dicyano-1,4- benzoquinone. Copyright
