1091613-52-3Relevant academic research and scientific papers
Use of libraries to access new chemical space: Applications to CRTH2
Masood, M. Abid,Gardner, Mark,Dack, Kevin,Winpenny, David,Lunn, Graham
scheme or table, p. 3682 - 3687 (2012/07/27)
The generation of novel CRTH2 ligands in heavily congested chemical space, by de novo design of libraries is disclosed. Novel (1719) compounds across seven libraries were synthesised. More than 100 of these compounds showed binding potency a viable one.
