1091629-06-9Relevant academic research and scientific papers
S-TRIAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME
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Page/Page column 37, (2009/01/20)
Novel s-triazine compounds are disclosed and represented by the following: formula (Ia). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, where microbial infection is either a direct cause or a related condition.
Synthesis and biological evaluation of novel 1,3,5-triazine derivatives as antimicrobial agents
Zhou, Chunhui,Min, Jaeki,Liu, Zhigang,Young, Anne,Deshazer, Heather,Gao, Tian,Chang, Young-Tae,Kallenbach, Neville R.
, p. 1308 - 1311 (2008/09/19)
Numerous studies have contributed to the development of natural and synthetic antimicrobial peptides as a prospective source of antibiotic agents. Based on the concept that cationic charge, bulk, and lipophilicity are major factors determining antibacterial activity in these peptides, we designed and screened several combinatorial libraries based on 1,3,5-triazine as a template. A set of compounds were identified to show potent antimicrobial activity together with low hemolytic activity.
