1092-04-2

Basic information

• Product Name: Estr-4-en-3-one, 17.beta.-hydroxy-2.alpha.-methyl-
• Synonyms: Estr-4-en-3-one, 17.beta.-hydroxy-2.alpha.-methyl-;17beta-hydroxy-2alpha-methylestr-4-en-3-one
• CAS NO: 1092-04-2
• Molecular Formula: C19H28O2
• Molecular Weight: 0
• Mol File: 1092-04-2.mol

Chemical Properties

• Boiling Point: 439.4°C at 760 mmHg
• Flash Point: 187.3°C
• Appearance: /
• Density: 1.11g/cm³
• Vapor Pressure: 1.44E-09mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: Estr-4-en-3-one, 17.beta.-hydroxy-2.alpha.-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Estr-4-en-3-one, 17.beta.-hydroxy-2.alpha.-methyl-(1092-04-2)
• EPA Substance Registry System: Estr-4-en-3-one, 17.beta.-hydroxy-2.alpha.-methyl-(1092-04-2)

Safety Data

• Hazardous Substances Data: 1092-04-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Estr-4-en-3-one, 17.beta.-hydroxy-2.alpha.-methylis used as a pharmaceutical intermediate for the synthesis of various steroidal drugs. Its unique structure allows it to serve as a key component in the development of medications targeting hormonal imbalances, inflammatory conditions, and other steroid-related health issues.
Used in Research and Development:
In the field of research and development, Estr-4-en-3-one, 17.beta.-hydroxy-2.alpha.-methylis utilized as a chemical entity for studying the properties and mechanisms of steroidal compounds. This helps scientists to better understand the role of steroids in biological systems and develop new therapeutic approaches for various diseases.
Used in Steroid Hormone Production:
Estr-4-en-3-one, 17.beta.-hydroxy-2.alpha.-methylis used as a precursor in the production of steroid hormones. Its specific structural features make it a valuable component in the synthesis of hormones such as estrogens and androgens, which play crucial roles in the regulation of various physiological processes in the body.
Used in Cosmetic Industry:
In the cosmetic industry, Estr-4-en-3-one, 17.beta.-hydroxy-2.alpha.-methylmay be used as an active ingredient in anti-aging and skin care products. Its steroidal nature could potentially contribute to the improvement of skin elasticity, hydration, and overall skin health.

InChI:InChI=1/C19H28O2/c1-11-9-15-12(10-17(11)20)3-4-14-13(15)7-8-19(2)16(14)5-6-18(19)21/h10-11,13-16,18,21H,3-9H2,1-2H3/t11-,13+,14-,15+,16+,18+,19+/m1/s1

Upstream product

• 1425-10-1 19-nortestosterone acetate 
• 434-22-0 19-nortestosterone 
• 4787-54-6 2-Methyl-oestradiol-3-methylether 
• 15410-31-8 2-Methoxymethyl-oestradiol-3-methylaether 
• 3919-20-8 2β-Methyl-17β-hydroxy-oestr-4-en-3-on 
• 74-88-4 methyl iodide 

Relevant articles and documents

NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF

Provided herein are 19-nor C3, 3-disubstituted steroids of Formula (I) : and pharmaceutically acceptable salts thereof; wherein R1, R2, R3, and R4are as defined herein, and A is a heteroaryl ring system comprising 3 or 4 nitrogens as defined herein. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, convulsive disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, and tinnitus.

19-NOR NEUROACTIVE STEROIDS AND METHODS OF USE THEREOF

Provided herein are 3,3-disubstituted19-nor-steroidal compounds according to Formula(I): and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions,for example, treatment of sleep disorders, mood disorders,schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders,personality disorders,autism spectrum disorders, pain,traumatic brain injury, vascular diseases,substance abuse disorders and/or withdrawal syndromes, tinnitus, status epilepticus.

19-NOR C3,3-DISUBSTITUTED C21-N-PYRAZOLYL STEROIDS AND METHODS OF USE THEREOF

Provided herein are 19-nor C3,3-disubstituted C21-pyrazolyl steroids of Formula (I), and pharmaceutically acceptable salts thereof; wherein-, R1, R2, R3a, R3b, R4a, R4b, R5, R6, and R7are as defined herein. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, convulsive disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, and tinnitus.